Januvia (Janumet) And Pancreatic Cancer

Posted by James GeorgeNov 21, 20190 Comments

The generic oral diabetes drug Januvia (sitagliptin) developed by Merck & Company to controls blood sugar levels in the body. The medicine is active because after consuming it, it controls the body's insulin levels. The diagnosis for Type II diabetes is accepted and does not function with Type I diabetes. The FDA approved this product alone or in combination with other diabetes drugs in October 2006.

Janumet is a prescription medicine brand name which includes metformin and sitagliptin. For individuals with type 2 diabetes, it is used together with diet and exercise to lower blood glucose. You do not usually make or use hormone insulin if you have type 2 diabetes, so it is unable, in your body, to control the amount of sugar or glucose. Metformin is in the class of pharmaceuticals called biguanides. Biguanides are three factors that decrease your blood-sugar levels and decrease liver insulin, decrease sugar absorption, and increase the amount of sugar consumed by your muscle cells.

Was Janumet liable for pancreatic cancer?

Were you afraid that Janumet caused you or your loved one to grow pancreatic cancer? If so, by filing a Janumet lawsuit, you may be entitled to recover damages. Researchers continue to investigate whether Janumet causes cancer of the pancreas. However, in Janumet sitagliptin was associated with 16 pancreatic cancer reports and 88 pancreatitis cases (linked a risk factor for pancreatic cancer). The fact that many people were not informed of this potential risk was troubling with our Janumet legal counsel.

Scientists don't know if Janumet causes cancer of the pancreas for sure. It is challenging to study Janumet pancreatic cancer since pancreatic cancer is extremely rare, and Janumet has not been marketed since 2007. In the course of a long-term analysis of sitagliptin and the pancreas, the FDA questioned Amylin Pharmaceuticals, the drugmaker behind sitagliptin. Current studies are in progress, and it will likely take many years to complete.

Pancreatic cancer risk factors include: 

Janumet: This drug and other GLP-1 treatment drugs specifically target pancreas cells.

Pancreatitis: persistent or severe swelling in the pancreas. Age: For people, over the age of 50 nearly all instances of pancreas cancer arise, and the incidence increases with age.

Obesity. Diabetes. Adipose. Liver issues: chronic diseases of the liver, such as liver cirrhosis. Diet: Some research has shown that high-fat diets, fried and transformed foods and/or smoked meats increase the risk of pancreatic cancer.

In 2011, a study of UCLA scientists published reported 16 cases of pancreatic cancer in patients with sitagliptin between 2004 and 2009.

In a 2009 letter of notice to the FDA, Janumet was linked with 88 instances of acute pancreatitis. The risk of developing pancreatic cancer is pancreatitis.

Pancreas cancer Causes: Cells that mutate and start to multiply out of control cause all cancers. Which triggers such mutations, though, remains unclear? Endocrine (hormone making) or exocrine (enzyme-making) cells in the pancreas may trigger the pancreas to become pancreas cancer. Endocrine cancer of the pancreas is less common than exocrine cancer of the pancreas, but the prediction is higher.

Janumet's Typical Side Effects: 

Tell your doctor whether any of the following effects is serious or not: moderate vomiting, diarrhea, constipation, or stomach discomfort. In the mouth, chemical flavor. Failure. Pain or muscle pain. Back pain. Hot, wet, runny, or sore throat signs.

More information about Janumet and pancreatic cancer:

Janumet is an oral medicine for sitagliptin and metformin that help to control blood sugar levels. Metformin decreases the production of glucose (sugar) in the liver and the absorption of glucose from the gut. Sitagliptin controls the body's insulin levels after you feed. For patients who do not use daily injections of insulin, the mixture is used to control type 2 diabetes. Janumet is not used for type 1 diabetes treatment. Janumet's typical adverse effects include runny or stuffy nose, cough, fatigue, moderate nausea, vomiting, diarrhea, gasses, and stomach pain. For Janumet, severe side effects can happen.

Janumet helps manage diabetes, and high sugar beverages/lifestyles will decrease the drug, and alcohol can be a significant factor, as prolonged use can increase the risk of lactic acidosis. Disease, stomach pain, myalgia, drowsiness, breathing disturbance, irregular heart rhythm, and hyperventilation are common symptoms. Because of this issue, alcohol with this medication is not advised.

Rarely, a serious side effect called lactic acidosis has been reported by some people when taking metformin. Stop taking Janumet and call for medical attention in the case of any lactic acidosis signs. These include weakness, sleepiness, slow heart rate, coolness, muscle pain, breathlessness, stomach pain, lightheadedness, and fainting. This is not a complete list of likely side effects of Janumet.

Janumet Lawsuit Information

Several patients are filing lawsuits focused on the supposed link between Januvia, a brand name diabetes, or sitagliptin in a generic form and pancreatic cancer growth. The association is particularly problematic for clinicians since pancreatic cancer is usually a potentially deadly malignancy that has no established successful medical treatment. 

Prospective lawyers in the area of litigation against Januvia have argued that Merck and Company realized the medication was faulty. Pancreatic cancer was increasingly likely in patients taking the drug. 

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