In addition to an increased risk for pancreatitis, pancreatic cancer, and other health problems, Byetta is a two-time injectant drug prescription for people with diabetes to control the levels of blood sugar. Byetta manufacturers have failed to correctly test the side effects of their medicinal products before requesting sales approval, according to lawsuits filed against the drug manufacturers Amylin Pharmaceuticals, Inc. and Bristol-Myers Squibb. The drugmaker failed to provide adequate warning about its hazards for doctors and consumers when discovered problems with Byetta.
In April 2005, the FDA approved Byetta. It is part of a drug class called incontinent mimetics, which function by imitating the effect on the gastrointestinal tract of certain hormones. The stimulation of the secretion of insulin from the pancreatic cells helps reduce blood glucose levels. The drug was part of an aggressive marketing campaign, leading to the prescription of the drug by millions of people by their doctors.
Is Pancreatic Cancer Caused by Byetta?
Byetta can possibly cause cancer of the pancreas, but nobody knows for certain. Byetta addresses the impact of GLP-1 (a hormone which induces the pancreas to produce more insulin) on diabetes. Byetta may cause chronic pancreatic inflammation, also referred to as pancreatitis in some people. Pancreatitis is a cancer risk factor as inflammation leads to more significant cell growth and death, which increases the chance of a cancer-causing DNA mutation.
What Causes Cancer of The Pancreas?
Pancreatic cancer is a condition that affects the existence in which pancreas cells begin to split up out of reach. We develop tumors within the pancreas, which is an organ that contains hormones and proteins behind the abdomen. Such cells create tumors. Cancer arises as changes in the DNA of a cell change the instructions for separating and developing the cells. The origins of these variations to DNA are unclear. Chronic inflammation, though, is a risk factor since cells are more fragmented than they usually have been.
Non-clinical studies have shown that incretin therapies can lead to increased cell proliferation. Such results, together with global studies of pancreatic cancer, raise concerns regarding the potential risk of developing pancreatic cancer by using these drugs in clinicians with incretin-based therapies.
Pancreatic cancer has a five-year relative survival of 8 percent, the fourth leading cause of cancer death in Canada. Smoking, obesity, the family history of the pancreas, chronic pancreatitis, and diabetes include but are not the only risk factors for pancreatic cancer.
SC focused on the global use of exenatide in pancreatic cancer patients but did not occur in any situation in Canada during the period in 2013. On 31 July 2014, Health Canada provided procedures in 13 cases of pancreatic cancer accused of affecting specific incontinent processes. Health Canada has not identified the causal relationship between incretin-based therapy and the production of PC based on available data.
Risks of Byetta Pancreatitis:
The FDA sent an alert to healthcare professionals in October 2007 to warn the company that obtained at least 30 records of acute pancreatitis complications after the use of Byetta ink.
A second alert issued in August 2008 in which informed health care providers of six new cases of Byetta pancreatitis necrotizing or hemorrhagic pancreatitis, which resulted in at least two deaths. Amylin Pharmaceuticals then recognized that they had noticed at least four other Byetta deaths among drug users linked to severe cases of pancreatitis.
Pancreatitis causes pancreatic inflammation, which can lead to treatment, infections in the long term, leukemia, or even death.
Hemorrhagic pancreatitis is a severe form of the disease in which massive blood vessel destruction can contribute to bleeding. Tissue-related injury triggering the release of toxins and enzymes into the bloodstream inducing multi-organ dysfunction is consistent with necrotic pancreatitis.
Byetta Gastrointestinal Side Effects:
The presence of pancreatitis was not long after Byetta was launched. Given the connection between pancreatitis and the creation of pancreatic cancer, drug manufacturers had not informed patients of this potential problem.
Byetta patients are advised to immediately contact their doctors and avoid using Byetta once signs of pancreatitis are established.
In the autumn of 2007, the FDA issued a warning to consumers of the medication that at least 30 patients were hospitalized with acute pancreatitis after several incident reports regarding Byetta. It has been confirmed by the FDA that an alert has been issued in Byetta following six further cases of necrotizing pancreatitis or hemorrhagic pancreatitis. Two of these events have been deadly at least.
In contrast to recorded cases of Byetta complications, individual reports of side effects while taking the medication continue to flood online message boards.
A person who was treated with Byetta in 2006 saw his blood sugar level reduced but had to be used many hours a day with antidiarrheal medications. He had to go into the hospital and was vomiting, nauseous, disoriented, and dizzy. Another person reported serious stomach issues after taking Byetta and was recently diagnosed with pancreatic cancer.
Evidence associates Byetta to Pancreatic Cancer. Although a definite causal association between Byetta and pancreatic cancer isn't formally established, those acquainted with the negative effects of the drug think the risk of developing cancer is serious as a consequence of the drug's potential to cause permanent inflammation of the pancreas.
One study published in Gastroenterology, February 2011, showed the incidence of pancreatic cancer in people taking Byetta three times higher than those who do not use the medication.
Do I have a Lawsuit with Byetta?
If you or someone you love is suffering from pancreatitis or pancreatic cancer after taking Byetta, you may be entitled to compensation. You can call our counsel directly for a free case review when you or someone you meet is diagnosed with pancreatic cancer.
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